The number of people who had annual prescription medication costs of $50,000 or more in 2016 was 35% higher than it was in 2014, according to pharmacy benefit manager (PBM) Express Scripts. The company’s new report, Super Spending: US Trends in High-Cost Medication Use, indicates that nearly 0.3% of Express Scripts members had annual medication costs at or greater than $50,000 in 2016. While 0.3% seems like a very small population, the company notes, it accounted for 21.3%